Multiple Sclerosis - Jun 5, 2023 - Unlocking the secrets of multiple sclerosis progression: Brain-immune cell communication

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	Multiple Sclerosis
	The latest multiple sclerosis news from News Medical

	Unlocking the secrets of multiple sclerosis progression: Brain-immune cell communication To commemorate World Multiple Sclerosis (MS) Day, we speak to Dr. Cameron McAlpine about his latest research that sought to understand better the proteins and signals that act as messengers between brain and immune cells in MS.

	Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

			Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development Epstein-Barr virus (EBV) has a significant role in the development of multiple sclerosis (MS), with evidence linking EBV infection to increased MS risk and immune dysregulation. Understanding the mechanisms underlying this connection is crucial for advancing MS therapies and prevention strategies.

			Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.

	Importance of analyzing the impact of life stressors on those with MS A Michigan Medicine-led study finds that stressors across the lifespan -; including poverty, abuse and divorce -; are associated with worsening health and functional outcomes for people with multiple sclerosis.

	This panel will decide whose medicine to make affordable. Its choice will be tricky. Catherine Reitzel's multiple sclerosis medication costs nearly $100,000 a year. Kris Garcia relies on a drug for a blood-clotting disorder that runs $10,000 for a three-day supply. And Mariana Marquez-Farmer would likely die within days without her monthly $300 vial of insulin.

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