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Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Study demonstrates that SARS-CoV-2 infection and viral fusogens cause glial and neuronal fusion.

9 Jun 2023

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

UBQLN2 dysfunction in ALS leads to elevated PEG10 levels, suggesting a role for retrotransposon activity in the disease. PEG10's nuclear localization alters gene expression involved in axon remodeling, implicating it as a contributing mechanism in ALS.

7 Jun 2023

Study reveals intricate pathway that dictates the cell’s ability to be resilient and plastic

Researchers have long thought that once a cell starts down its path of differentiation, growing into a skin cell or a liver cell or a neuron, that path could not be changed.

7 Jun 2023

Immune system's ability to respond to spinal cord injuries diminishes with age, study suggests

New research suggests that the immune system's ability to respond to spinal cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

2 Jun 2023

Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles.

1 Jun 2023

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

This new article publication from Acta Pharmaceutica Sinica B, discusses click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries.

31 May 2023

Ultraflexible nanoelectrodes improve the efficacy of brain stimulation

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

30 May 2023

Research could help develop better treatments for swallowing disorders

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.

26 May 2023

Fast and accurate automatic neuron reconstruction using 3D images

Dr. Shuiwang Ji, a professor in the Department of Computer Science and Engineering at Texas A&M University, is part of a collaborative research community that recently had its paper titled "BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets" published in the April issue of the journal Nature Methods.

26 May 2023

UQ neuroscientists uncover how vitamin D deficiency affects developing neurons in schizophrenia

Neuroscientists at The University of Queensland have uncovered how vitamin D deficiency affects developing neurons in schizophrenia, using new technology.

25 May 2023

Immune system’s ability to respond to spinal cord injuries reduces with age, research suggests

New research suggests that the immune system’s ability to respond to spinal-cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

25 May 2023

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

To produce its many functions, including thought, the brain works at many scales. Information such as goals or images is represented by coordinated electrical activity among networks of neurons, while within and around each neuron a mix of proteins and other chemicals physically carries out the mechanics of participating in the network.

22 May 2023

Gamma frequency tactile stimulation can reduce Alzheimer's disease pathology and symptoms

Evidence that non-invasive sensory stimulation of 40 Hz gamma frequency brain rhythms can reduce Alzheimer's disease pathology and symptoms, already shown with light and sound by multiple research groups in mice and humans, now extends to tactile stimulation.

18 May 2023

Glycosylation enzyme plays a crucial role in brain development, study shows

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

16 May 2023

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

The cerebellum, a major part of the hindbrain in all vertebrates, is important for motor coordination, language acquisition, and regulating social and emotional behaviors.

15 May 2023

Study reveals how serotonin affects animal behavior at the whole-brain scale

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

15 May 2023

Study offers new insights into how toxic proteins spread in the brains of people with Alzheimer's disease

Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer's disease could hold the key to stopping the condition progressing, a study says.

15 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

Same genetic defects shared by some patients with motor neuron disease and frontotemporal dementia

New research has discovered that some patients with motor neuron disease (MND) and frontotemporal dementia (FTD) carry the same rare genetic defects that cause other neurodegenerative diseases.

9 May 2023

Study shows the power of gamma enhancement as potential approach for countering depression

Led by researchers from NYU Grossman School of Medicine and Hungary's University of Szeged, a new study in mice and rats found that restoring certain signals in a brain region that processes smells countered depression.

9 May 2023

Neuron News and Research

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

Study reveals intricate pathway that dictates the cell’s ability to be resilient and plastic

Immune system's ability to respond to spinal cord injuries diminishes with age, study suggests

Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

Ultraflexible nanoelectrodes improve the efficacy of brain stimulation

Research could help develop better treatments for swallowing disorders

Fast and accurate automatic neuron reconstruction using 3D images

UQ neuroscientists uncover how vitamin D deficiency affects developing neurons in schizophrenia

Immune system’s ability to respond to spinal cord injuries reduces with age, research suggests

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

Gamma frequency tactile stimulation can reduce Alzheimer's disease pathology and symptoms

Glycosylation enzyme plays a crucial role in brain development, study shows

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

Study reveals how serotonin affects animal behavior at the whole-brain scale

Study offers new insights into how toxic proteins spread in the brains of people with Alzheimer's disease

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

Same genetic defects shared by some patients with motor neuron disease and frontotemporal dementia

Study shows the power of gamma enhancement as potential approach for countering depression

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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