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Protecting the heart during menopausal transition may help protect brain health

The research, published in the journal Alzheimer's & Dementia, is further evidence that the menopause transition is a particularly important time for women and their doctors to pay attention to heart health, in turn protecting their brain health.

5 Jun 2023

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study explores the effects of a green-MED diet enriched in polyphenols and reduced in red/processed meat on the methylome and transcriptome levels. It aims to uncover the molecular mechanisms underlying the observed metabolic improvements.

30 May 2023

Using ex vivo gene therapy to fight obesity and diabetes in mice

A scientific team from the University of Barcelona and the CIBERobn has designed a strategy to fight obesity and diabetes in mice through ex vivo gene therapy which consists of implanting cells that have been manipulated and transformed in order to treat a disease.

30 May 2023

Obesity strikes below the belt: Study reveals link between obesity and male infertility

The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.

29 May 2023

UTHealth Houston receives federal funding for traumatic brain injury research

Nearly $13 million in federal grant funds to study treatments for traumatic brain injury, which kills an average of 190 people and hospitalizes another 600 in the U.S. every day, has been awarded to UTHealth Houston by the Department of Defense's Office of Congressionally Directed Medical Research Programs (CDMRP).

25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

Investigating the interplay between white blood cell count and incidence of hyper-low-density lipoprotein cholesterolemia

Researchers investigating the association between white blood cell count and LDL hypercholesteremia.

24 May 2023

Gut check: Our microbiome's vitamin factory could redefine personal health

Research highlights the crucial role of vitamins in metabolic and regulatory processes. It explores the microbial contribution of essential vitamins, such as vitamin K and B-group vitamins, in the gastrointestinal tract, emphasizing their impact on human health and the gut microbiome.

23 May 2023

Whole body cryostimulation: Useful "add-on" treatment for obesity

Whole body cryostimulation is a useful "add-on" treatment for obesity, research being presented at the European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May) suggests.

19 May 2023

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Nearly half of all cancer patients suffer from excessive weight loss due to the loss of adipose and skeletal muscle tissues, or cachexia.

18 May 2023

Is there an association between long-term plasma caffeine intake and adiposity, type 2 diabetes, and cardiovascular diseases?

Investigate the effects of long-term exposure to higher plasma caffeine concentrations on T2D, adiposity, and cardiovascular diseases.

18 May 2023

What is the association between obesity and insulin resistance in youth and its production of colon-derived acetate, gut-derived hormone secretion, and adipose tissue lipolysis?

Researchers assessed whether insulin resistance and adiposity in youth were linked to the fermentation of dietary fibers.

11 May 2023

Maintaining a healthy weight could reduce future gastrointestinal cancer risk

Doctors have long stressed the importance of maintaining a healthy weight for improving overall health, but a large new study also suggests it could also reduce future gastrointestinal cancer (GI) risk.

10 May 2023

Environmental PAH exposure associated with increased rheumatoid arthritis risk

The amount of environmental exposure to polycyclic aromatic hydrocarbons, or PAH for short, is strongly linked to a person's risk of developing rheumatoid arthritis, suggests research published in the open access journal BMJ Open.

10 May 2023

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

In this study, the effects of a high-fat diet on the formation of bisretinoids in photoreceptor cells were explored. The results showed that mice on a high-fat diet had increased levels of bisretinoids and retinol-binding protein 4, which are associated with metabolic dysregulation.

8 May 2023

Study uncovers a crucial player for enhancing lipid oxidation

Overweight and obesity pose significant health risks, including an increased likelihood of developing diabetes, cardiovascular disease, and cancer.

8 May 2023

High-dose drug for erectile dysfunction improves long-term blood sugar levels in diabetes patients

A small group of patients with type 2 diabetes significantly improved their long-term blood sugar levels when treated with high-dose tadalafil, a medication used to treat erectile dysfunction.

5 May 2023

Does stress increase biological age?

Researchers evaluated stress-induced biological age (BA) changes among mice and humans.

4 May 2023

What are the benefits of exercise on cardiovascular health?

Researchers estimated the impact of exercise on cardiovascular (CV) health.

1 May 2023

Shedding light on diabetes: Vitamin D's crucial role in insulin regulation and disease prevention

Research discusses the role of vitamin D in both type 1 and type 2 diabetes pathogenesis. It summarizes the molecular mechanisms of vitamin D in insulin secretion, insulin sensitivity, and immunity, as well as the observational and interventional human studies investigating the use of vitamin D as a treatment for diabetes.

25 Apr 2023