Tetanus News and Research

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Tetanus is a severe, frequently fatal disease caused by an exotoxin produced by Clostridium tetani, a bacterium that is found in the environment. Tetanus is not transmitted from person to person. Rather, Clostridium tetani enters the body through an open wound, including lacerations, abrasions and puncture wounds. The toxin causes neuromuscular dysfunction, with rigidity and spasms of skeletal muscles. The muscle spasms usually start in the jaw (which is why the disease is sometimes called "lockjaw") and neck and may spread to many other muscles, leading to generalized paralysis.

Study reveals factors impacting pertussis antibody half-lives in infants, sheds light on preterm infants' resilience

Researchers compared two methods of half-life estimation to evaluate the half-life of maternal antibodies.

9 Jun 2023

How the mixed messaging of vaccine skeptics sows seeds of doubt

It was a late-spring House of Representatives hearing, where members of Congress and attendees hoped to learn lessons from the pandemic. Witness Marty Makary made a plea.

8 Jun 2023

Vaccination coverage drops in U.S. schools, raising concerns of outbreaks

Research highlights the decline in national coverage of state-required vaccines among kindergarten students during the 2020-2021 and 2021-2022 school years. Despite a low exemption rate, vaccination coverage decreased further in the latter year, indicating ongoing COVID-19 disruptions and emphasizing the need for increased follow-up with under-vaccinated students to protect against vaccine-preventable diseases.

22 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Research paper reports the results of a phase 3 clinical trial evaluating the efficacy and safety of the FINLAY-FR-2 and FINLAY-FR-1A vaccines in Iranian adults.

7 May 2023

Advancing the development of vaccines through recombinant technology

In this interview, News-Medical talks to Dr. Amy Sheng, the head of CRO at Sino Biological, about current developments in the field of vaccine development through recombinant techniques.

From Sino Biological Inc. 4 May 2023

A high proportion of adults in Europe do not have protective antibody concentrations against diphtheria

Researchers conducted a retrospective analysis of seroprotection against tetanus and diphtheria among residents in Austria.

1 May 2023

Adherence to national guidelines for childhood vaccination on the rise, study shows

The percentage of children under 19 months who received all recommended vaccines on-time steadily improved from 22.5% in 2011 to 34.9% in 2020, according to a new national study.

28 Apr 2023

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

The newly developed DCFHP-alum COVID-19 vaccine candidate is affordable and effective for mass vaccination.

18 Apr 2023

Low vaccine coverage fuels recurrence of diphtheria in Nigeria

Low vaccine coverage and weak infrastructure have fuelled a recurrence of diphtheria in Nigeria, especially in rural areas beset by poor access to healthcare services, public health experts say.

28 Mar 2023

Montana considers new wave of legislation to loosen vaccination rules

When Deb Horning's youngest daughter was 5, she got her measles, mumps, and rubella shot like many other kindergartners. But unlike many other moms, Horning had to stay away from her daughter for a week after the shot.

10 Mar 2023

A technicality could keep RSV shots from kids in need

After more than five decades of trying, the drug industry is on the verge of providing effective immunizations against the respiratory syncytial virus, which has put an estimated 90,000 U.S. infants and small children in the hospital since the start of October.

6 Feb 2023

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Researchers evaluated immunoglobulin G (IgG) responses to coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccinations.

20 Jan 2023

Oxford's Ebola vaccine candidate manufactured and shipped to Uganda in just 80 days

Oxford's Ebola vaccine candidate has been shipped to Uganda, just 80 days after WHO declared a Sudan ebolavirus outbreak, having been manufactured by its partner the Serum Institute of India and working in close partnership with WHO.

5 Jan 2023

Vaccination against pertussis in pregnancy and outstanding scientific questions

A recent paper published in Vaccines summarized the data presented and the discussions in the meeting regarding pertussis vaccination in pregnancy (ViP).

2 Dec 2022

Antibody responses engendered by maternal SARS-CoV-2 vaccination following initial and booster doses in maternal circulation and breastmilk

Researchers investigated passive immunization of the fetus and neonates by evaluating the antibody responses elicited by primary and booster doses of maternal SARS-CoV-2 vaccination.

2 Dec 2022

Impact of an individually tailored educational application on vaccine attitudes of pregnant women and mothers

Researchers evaluated the impact of MomsTalkShots, a personalized application, on maternal attitudes toward vaccinations.

29 Nov 2022

Is placental antibody transfer after COVID-19 vaccination different from that after SARS-CoV-2 infection in pregnant individuals?

Researchers investigated the placental transfer ratios of anti-SARS-CoV-2 antibodies in pregnant females.

11 Nov 2022

Updated EULAR recommendations for children with pedAIIRD

People with autoimmune or auto-inflammatory rheumatic diseases have an increased risk of infections. This can be due to the underlying disease itself, or may be caused by treatment with immunomodulating or immunosuppressive drugs.

28 Oct 2022

Study reveals immune characteristics of long-COVID

Researchers perform antibody profiling against SARS-CoV-2, several endemic pathogens, as well as vaccine antigens among rheumatic disease patients.

2 Oct 2022