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Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Study demonstrates that SARS-CoV-2 infection and viral fusogens cause glial and neuronal fusion.

9 Jun 2023

Investigating the alveolar type II reparative response in COVID-19 pneumonia

Researchers investigated the alveolar type II reparative response in COVID-19 pneumonia.

9 Jun 2023

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

In a review article published in the journal Signal Transduction and Targeted Therapy, scientists have discussed host metabolic alteration triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its effect on disease severity.

9 Jun 2023

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome.

8 Jun 2023

Scientists unlock virus-fighting power with synthetic nanobody platform

Discovery and validation of nanobodies, a promising class of biologics, for viral infection prevention and treatment, including anti-SARS-CoV-2 nanobodies with enhanced neutralization properties through synergistic pairing. The study demonstrates the potential of nanobodies in developing effective therapies against viral infections.

8 Jun 2023

Biologists discover a previously unknown way that the immune system detects viruses

Inflammasomes make up an intricate system of molecular sensors that our bodies use to sound an alarm when an infection occurs.

8 Jun 2023

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Researchers in the Hermelin Brain Tumor Center at Henry Ford Health are leading a Phase I clinical trial studying the maximum tolerated dose of an oncolytic adenovirus, a mutated virus engineered to selectively replicate in and destroy cancer tissue, in combination with fractionated stereotactic radiosurgery among patients who are undergoing resection of a recurrent high-grade astrocytoma brain tumor.

8 Jun 2023

Cryo-EM reveals key atomic structures of the ends of actin filament

Actin filaments -; protein structures critical to living movement from single cells to animals -; have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ends.

8 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Study uncovers novel mechanisms underlying plant immunity against major root disease

Researchers led by CHEN Yuhang and ZHOU Jianmin from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown how plants resist clubroot, a major root disease that threatens the productivity of Brassica crops such as rape.

8 Jun 2023

Study shows how blood makes the brain’s immune cells toxic

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive dysfunction and motor impairment.

8 Jun 2023

Study provides a new perspective on the aberrant nature of B cell phenotypes in skin cancer

A new study that sheds light on how B cells react to skin cancer cells could pave the way for innovative therapy design.

8 Jun 2023

DNA study sheds light on how we maintain healthy blood sugar levels after meals

A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process goes wrong in type 2 diabetes.

8 Jun 2023

Penn Medicine researchers receive $6 million NIH grant to gain new insights on cardiac cellular identity

Historically, scientists have studied how cells develop and give rise to specialized cells, such as heart, liver, or skin cells, by examining specific proteins.

8 Jun 2023

Weak spot discovery could pave way for more effective cancer therapies

Prostate cancer is the most common non-skin cancer in men worldwide. According to international estimates about one in six men will get prostate cancer during their lifetime and worldwide, over 375'000 patients will die from it each year.

8 Jun 2023

Scientists identify the IL-17 protein as a determining factor in skin aging

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin aging.

8 Jun 2023

Damon Runyon and St. Jude announce a new pediatric-focused fellowship

The Damon Runyon Cancer Research Foundation and St. Jude Children's Research Hospital announced a new pediatric-focused fellowship today.

8 Jun 2023

University Hospital Centre for Emerging Viral Diseases named as a WHO collaborating center for epidemic and pandemic diseases

The World Health Organization (WHO), the University of Geneva (UNIGE) and Geneva University Hospitals (HUG), yesterday formalized the designation of the University Hospital Centre for Emerging Viral Diseases as a WHO collaborating center for epidemic and pandemic diseases.

8 Jun 2023

H.E.L Group expands range of BioXplorer bioreactors to support bioprocess development

H.E.L Group (H.E.L), a global developer and manufacturer of innovative laboratory tools for process optimization.

From H.E.L Group 8 Jun 2023

Study shows Alzheimer’s disease-associated retinopathy can be ameliorated by dietary lysophosphatidylcholine-EPA/DHA

Researchers evaluated the impact of dietary lysophosphatidylcholine (LPC), comprising eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on retinal function in Alzheimer’s disease (AD)-associated retinopathy.

8 Jun 2023

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Cell News and Research

Mechanistic insights into how the SARS-CoV-2 virus affects the nervous system, alters its function, and causes neuropathology

Investigating the alveolar type II reparative response in COVID-19 pneumonia

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

Scientists unlock virus-fighting power with synthetic nanobody platform

Biologists discover a previously unknown way that the immune system detects viruses

Study may help advance data on oncolytic adenovirus mediated double suicide-gene therapy for high-grade brain tumors

Cryo-EM reveals key atomic structures of the ends of actin filament

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Study uncovers novel mechanisms underlying plant immunity against major root disease

Study shows how blood makes the brain’s immune cells toxic

Study provides a new perspective on the aberrant nature of B cell phenotypes in skin cancer

DNA study sheds light on how we maintain healthy blood sugar levels after meals

Penn Medicine researchers receive $6 million NIH grant to gain new insights on cardiac cellular identity

Weak spot discovery could pave way for more effective cancer therapies

Scientists identify the IL-17 protein as a determining factor in skin aging

Damon Runyon and St. Jude announce a new pediatric-focused fellowship

University Hospital Centre for Emerging Viral Diseases named as a WHO collaborating center for epidemic and pandemic diseases

H.E.L Group expands range of BioXplorer bioreactors to support bioprocess development

Study shows Alzheimer’s disease-associated retinopathy can be ameliorated by dietary lysophosphatidylcholine-EPA/DHA

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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