Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.
Researchers evaluated the association between Helicobacter pylori and cognition.
Researchers investigated the alveolar type II reparative response in COVID-19 pneumonia.
A protein found in cells of the hard tick Amblyomma sculptum, the main vector of the bacterium that causes Brazilian spotted fever (also known as Rocky Mountain spotted fever), is essential to the tick's survival while feeding, making it a promising target for development of a vaccine, according to an article published in the journal Parasites & Vectors.
Early studies of COVID-19 focused on the acute phase of the disease. However, attention has now turned to the long-term consequences of the disease, which are also significant causes of morbidity and mortality.
Acute myeloid leukemia (AML) is a very aggressive disease in which cells proliferate abnormally, invading the bone marrow and interfering with normal blood cell production. It is the most common acute leukemia in adults with the worst prognosis.
Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion.
Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.
Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.
The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.
Researchers review existing data on the impact of phthalate exposure on cardiovascular health.
Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.
Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.
A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Targeting cellular respiration as a therapeutic strategy in glioblastoma."
Identifying the underlying mechanism associated with the initiation of focal amplification in breast cancer.
This review highlights carotenoids' various biological activities, including antioxidant, anti-tumor, anti-diabetic, anti-aging, and anti-inflammatory effects, with a specific focus on lycopene.
Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.
A study explores the role of the dynamin protein DYN-1 in axonal fusion. The axon is a long, thin protrusion of nerve cells that carries electrical impulses.
Researchers aimed to understand how exposure to cigarette smoke causes alterations in bone structure.
A new research perspective was published in Oncoscience (Volume 10) on April 4, 2023, entitled, "Mitochondrial regulator ATAD3A: a molecular determinant favoring head and neck cancer development."
Scientists from the Immanuel Kant Baltic Federal University found out that blocking of receptor gp130 on the surface of liver cells helps to protect this organ from destruction in case of obesity.