HIV/AIDS - Jun 6, 2023 - First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses

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	HIV/AIDS
	The latest HIV/AIDS news from News Medical

	First-in-human nanoparticle HIV vaccine induces broad and publicly targeted helper T cell responses Researchers from Fred Hutchinson Cancer Center in Seattle, Scripps Research in La Jolla, California, IAVI and other collaborating institutions have characterized robust T-cell responses in volunteers participating in the IAVI G001 Phase 1 clinical trial to test the safety and immune response of a self-assembling nanoparticle HIV vaccine.

	New method may help identify the essential ingredients for making an effective HIV vaccine Since it was identified in 1984 as the cause of Acquired Immune Deficiency Syndrome (AIDS), the human immunodeficiency virus (HIV) has infected more than 80 million people and been responsible for some 40 million deaths worldwide, according to the World Health Organization (WHO).

			Nonhuman primate study helps explain how stem cell transplantation can kill HIV virus New animal research is helping explain why at least five people have become HIV-free after receiving a stem cell transplant.

			Antiviral drugs may be a new treatment strategy in the fight against Candida auris Antiviral drugs can make antifungals work again.

			$11.6 million NIDA grant supports the study of cannabis effects on HIV-infected brains Weill Cornell Medicine has been awarded a five-year, $11.6 million grant from the National Institute on Drug Abuse of the National Institutes of Health to study the effects cannabis, including marijuana and compounds derived from it, may have on the brains of those living with HIV.

	Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation Novel EABR technology enhances potency and breadth of vaccine-induced responses through antigen presentation.

	Looking at cancer drugs to help put the brakes on classic indicators of aging Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

	Immune cells targeting core protein play an important role in early immune defense against COVID-19 LMU immunologists have studied the early immune response to acute SARS-CoV-2 infection and show how vaccines could be improved in future.

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